houston mesothelioma lawyers

Cancer is a very hot topic in scientific research today by the apparent lack of knowledge of certain underlying biological processes. Without the mastery of these biological pathways, it is not possible to surefire treatment and / or methods of prevention against developing certain types of cancer. You do not have very far to find criticism or find an attempt at exploitation of these biological cavities through the media. Despite the frequent monitoring, (in the field of oncology, theUnderstand exponentially study of tumors / cancer), the manifestation, diagnosis, prevention and improved treatment of cancer. A simple look at the declining morbidity among cancer patients in recent decades should provide some comfort, even skeptical about the man.

Despite the numerous advances in cancer research, manage the findings under the radar of the mainstream media to fly. It is in these small insights that are the basis for future applications andCures. Recently, a group of researchers a step closer to resolving their life-saving puzzle.

The study by researchers at UT-Houston MD Anderson Cancer Center and funded by the National Cancer Institute conducted, analyzed the destructive effects on the brain tumor stem cells of mice by introducing a custom adenovirus (Delta-24-RDG). Through customized adenovirus, I mean a specific virus by scientists produced. This has been tested on the most aggressive brain tumor, glioblastomamultiforme, which is known to confer resistance to chemotherapy and radiotherapy. The special fascination in this project arises from the attempt to known and studied research conducted in 2003 to build.

The 2003 study showed that Delta-24 eliminated brain tumors in 60% of the mice. The recent study conducted on the actual stem cells, however, that the continued growth of tumors after surgery take up the examination of glioma stem cells. This led to a direct comparison of survival betweenthe control group (receiving no intervention) and the treated group (receiving Delta-24-injection). The survival of the mice who have been treated almost doubled that of the control group. The result is clear: The mice that received the injection of the adenovirus showed longer lifetimes. The success of the study is not simply an end.

The researchers attempted to analyze more than just cause and effect. They tried to gain information about the actual physiologicalProcess, on the death of stem cells in the brain. For the first time that adenovirus-mediated cell death () by autophagy was found as a direct method of cell death in tumor cells of the brain. It was also noted that the therapeutic virus does not alter normal brain tissue. This realization brings with it tremendous hope, because the tumors formed in the brains of these mice closely resemble human tumors. This similarity lies in their irregular shape and invasiveor metastatic spread, characteristics. The study has to remember the limitations of these findings and the need for further research, but it is an exciting and possible method of cancer treatment, which should not be confined to the brain postulate. This study only hints of the remarkable and ongoing efforts to further cancer research. It must be remembered that our race for a cure is not a sprint, but a continuous marathon, must be carefully and methodically ran.

1) Fueyo J, Alemany R,Gomez-Manzano C, Fuller GN, Khan A, Conrad CA, Liu TJ, Jiang H, Lemoine MG, Suzuki K, Sawaya R, Curiel DT, Yung WK, Lang FF. Preclinical characterization of the antiglioma activity of a tropism-enhanced adenovirus targeted to the retinoblastoma path. J Natl Cancer Inst 2003 7. May 95 (9) :652-60. PMID: 12,734,316th

2) H. Jiang, C. Gomez-Manzano, H. Aoki, MM Alonso, S. Kondo, F. McCormick, J. Xu, Y. Kondo, Bekele BN, Colman H, Lang FF, Fueyo J. Examination of the therapeutic potentialDelta-24-RGD in brain tumor stem cells: the role of autophagic cell death. J Natl Cancer Inst 2007 Sep 19; 99 (18) :1410-4. PMID: 17,848,677th

My Links : Swine Flu Vaccine